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From: Webster's Revised Unabridged Dictionary (1913)

 Pes·ti·lence n.
 1. Specifically, the disease known as the plague; hence, any contagious or infectious epidemic disease that is virulent and devastating.
    The pestilence that walketh in darkness.   --Ps. xci. 6.
 2. Fig.: That which is pestilent, noxious, or pernicious to the moral character of great numbers.
    I'll pour this pestilence into his ear.   --Shak.
 Pestilence weed Bot., the butterbur coltsfoot (Petasites vulgaris), so called because formerly considered a remedy for the plague.