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From: Webster's Revised Unabridged Dictionary (1913)

 Prej·u·di·cial a.
 1. Biased, possessed, or blinded by prejudices; as, to look with a prejudicial eye. [Obs.]
 2. Tending to obstruct or impair; hurtful; injurious; disadvantageous; detrimental.
    His going away . . . was most prejudicial and most ruinous to the king's affairs.   --Clarendon.
 -- Prej*u*di*cial*ly, adv. -- Prej*u*di*cial*ness, n.