ups and downs
高低起落,坎坷不平,盛衰沈浮,有苦亦有樂
Up, n. The state of being up or above; a state of elevation, prosperity, or the like; -- rarely occurring except in the phrase ups and downs. [Colloq.]
Ups and downs, alternate states of elevation and depression, or of prosperity and the contrary. [Colloq.]
They had their ups and downs of fortune. --Thackeray.