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From: MDBG CC-CEDICT Chinese-English Dictionary 漢英字典

 坎坷多舛 [ㄎㄢˇ ㄎㄜˇ ㄉㄨㄛ ㄔㄨㄢˇ; kan3 ke3 duo1 chuan3]
 full of trouble and misfortune (usu. referring to someone's life)