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From: MDBG CC-CEDICT Chinese-English Dictionary 漢英字典

 脫胎換骨 [ㄊㄨㄛ ㄊㄞ ㄏㄨㄢˋ ㄍㄨˇ; tuo1 tai1 huan4 gu3]
 to shed one's mortal body and exchange one's bones (idiom); born again Daoist
 to turn over a new leaf
 fig. to change wholly
 to create from other material (story, artwork etc)